Sapient Discovery Technology Related Publications

The scientific founders of Sapient Discovery and the scientists in the Company have extensive record of publications, presentations, patents and patent applications. It is the goal of the company founders to continue to publish/present/patent new technology as well as exciting new results resulting from their work. In this section a sample is given of their publications. Where it is appropriate, a direct link is given to the journal website for downloading or accessing the publications. If you like a copy of any of the publications, you can also contact us at [email protected] and we will send you a hard copy of the requested article.


Protein Structure Prediction Using an Augmented Homology Modeling Method: Key Importance of Iterative-Procedures for Obtaining Consistent Quality Models

Current Proteomics 2, 233-258 (2005)

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08.04.2006

Structural analysis of an HIV-1 protease I47A mutant resistant to the protease inhibitor lopinavir

Protein Science 14:1870-1878 (2005)

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08.04.2006

Bioinformatics of Botulin Neurotoxin Structures.

Current Proteomics 1, 145-166 (2004).

08.04.2006

Tools for structural genomics: accelerating the structure pipeline

Drug Discovery World  Summer Issue, 65-74 (2004)

08.04.2006

Structure-based phenotyping predicts HIV-1 protease inhibitor resistance

Protein Science 12: 1706-1718 (2003)

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08.04.2006

Structure-based prediction of free energy changes of binding of PTP1B inhibitors.

J. Computer-Aided Molecular Design 17, 495–513 (2003)

08.04.2006

Structural Proteomics: Methods in Deriving Protein Structural Information and Issues in Data Management

Biotechniques: Computational Proteomics Supplement, 32:S42-S46 (2002)

08.04.2006

Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-a

Proc. Natl. Acad. Sci. 8, 11879–11884 (2001)

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08.04.2006

Recent developments in computational proteomics.

Trends in Biotechnology 19, 266-272 (2001)

08.04.2006

Structural Pharmacogenomic Approach to the Evaluation of Drug Resistant Mutations in HIV-1 Protease.

J. of Clinical Ligand Assay 24, 140-144. (2001)

08.04.2006

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